Hotel Sile is just two minutes from Termini station (main station).
When you are outside the train station exit on right side and go along Via Marghera. At the first corner after a restaurant called Da Nazzareno turn to right again and you are in Via Magenta. We are at number 39 on the 4th floor.
From the airport take the local train, there is one every 30 minutes to Termini station. It takes about 45 minutes.